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The MOCA I Study - Microvascular Obstruction with CoFI™ System Assessment

NCT03654573 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 73

Last updated 2025-03-19

No results posted yet for this study

Summary

First-in-Human study to assess the CoFI™ device related safety and the feasibility of the diagnostic and the therapeutic sequence as well as the correlation between the dynamic microvascular resistance (dMVR) and microvascular obstruction (MVO) as measured by MRI in patients presenting with acute ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI).

Conditions

  • STEMI - ST Elevation Myocardial Infarction
  • Microvascular Obstruction

Interventions

DEVICE

CorFlow Controlled Flow Infusion System - CoFI™

The CorFlow CoFI™ System is intended to assess the dynamic microvascular resistance and to treat microvascular obstruction in the coronary vasculature of patients following PCI with stent placement.

Sponsors & Collaborators

  • CorFlow Therapeutics AG

    lead INDUSTRY

Principal Investigators

  • Lukas Hunziker · Insel Gruppe AG, University Hospital Bern

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-06-04
Primary Completion
2024-12-18
Completion
2024-12-18

Countries

  • Lithuania
  • Switzerland
  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03654573 on ClinicalTrials.gov