High Intensity Interval Training (HIIT) for Patients With Cancer-related Lymphedema in the Lower Limbs

Summary

The aim of the study is to explore the feasibility and safety of High Intensity Interval Training on a stationary bike for patients with lymphedema in the lower limbs and the role of compression garments during exercise.

The design of the study is a cross-over randomized clinical trial. Participants will be randomized into two groups. Both will perform two separate exercise sessions.Group A will perform the first exercise with compression garment and the second session without compression garment, with wash-out period of 1 week between sessions. Group B will perform the exercise sessions in the opposite order.

Conditions

• Lymphedema of Leg
• Cancer of Cervix
• Cancer, Ovarian
• Cancer, Endometrial
• Cancer of the Prostate
• Malignant Melanoma

Interventions

OTHER

First exercise session + compression

The Interval Training consists of a 5 minute warm-up on the stationary bike followed by 7 intervals of cycling for 1 minute at level 15-16 on the Borg Scale of Perceived Exertion. Inbetween intervals, participants reduce resistance on the stationary bike and pedals for 1 minute at level 11-12 on the Borg Scale. The session ends with a 5-10 minute cool-down pedaling and stretching exercises for the lower limbs.

OTHER

First exercise session - compression

The Interval Training consists of a 5 minute warm-up on the stationary bike followed by 7 intervals of cycling for 1 minute at level 15-16 on the Borg Scale of Perceived Exertion. Inbetween intervals, participants reduce resistance on the stationary bike and pedals for 1 minute at level 11-12 on the Borg Scale. The session ends with a 5-10 minute cool-down pedaling and stretching exercises for the lower limbs.

Sponsors & Collaborators

• University of Copenhagen

  collaborator OTHER

• Herlev and Gentofte Hospital

  lead OTHER

Principal Investigators

• Merete C Wittenkamp, PT · Department of Physiotherapy and Occupational Therapy at Herlev and Gentofte Hospital,

• Carsten B Juhl, PT MPH PhD · Department of Physiotherapy and Occupational Therapy, Herlev and Gentofte Hospital/Research Unit for Musculoskeletal Function and Physiotherapy, University of Southern Denmark.

• Anders Vinther, PT MSc PhD · Department of Physiotherapy and Occupational Therapy, Herlev and Gentofte Hospital

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2018-09-06

Primary Completion

2018-11-13

Completion

2018-11-13

Countries

• Denmark

Study Locations