ATP and Capsaicin Cough Provocation Test in Chronic Cough and Bronchiectasis
NCT03638063 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2020-02-11
Summary
This is a randomized, cross-over, single-blind trial. Eligible patients will be randomly assigned to undergo either capsaicin or adenosine triphosphate (ATP) cough provocation test, followed by a washout period of 2 to 14 days. Participants will be crossed-over to undergo another cough provocation test. Patient would be under observation in the out-patient clinics for \~2 hours following the cough provocation tests in case of severe adverse events.
Conditions
- Chronic Cough
- Bronchiectasis
Interventions
- DIAGNOSTIC_TEST
-
Adenosine Triphosphate
Adenosine Triphosphate aerosol
- DIAGNOSTIC_TEST
-
capsaicin
capsaicin aerosol
Sponsors & Collaborators
-
Guangzhou Institute of Respiratory Disease
lead OTHER
Principal Investigators
-
Ke-fang Lai, MD · Guangzhou Institute of Respiratory Health Locations: China, Guangdong First Affiliated Hospital of Guangzhou Medical
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-10-29
- Primary Completion
- 2020-07-31
- Completion
- 2020-07-31
Countries
- China
Study Locations
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