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Predicting Ipsilesional Motor Deficits in Stroke With Dynamic Dominance Model

NCT03634397 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 58

Last updated 2025-09-12

Study results available
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Summary

This study will test the hypothesis that the combination of low-moderate to severe motor deficits in the paretic arm and persistent motor deficits in the less-impaired arm limits functional independence in chronic stroke survivors. We, therefore, predict that intense remediation, focused on improving the speed, coordination, and accuracy of the less-impaired arm should improve functional independence.

Conditions

Interventions

BEHAVIORAL

Less-Impaired Arm Training

Participants receive virtual reality and manipulation training in their less impaired arm.

BEHAVIORAL

Contralesional Arm Comparison

Participants receive therapy in their paretic arm, based on the best-practices framework for arm recovery post stroke.

Sponsors & Collaborators

  • University of Southern California

    collaborator OTHER

  • Penn State University

    collaborator OTHER

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    collaborator NIH

  • Robert L. Sainburg

    lead OTHER

Principal Investigators

  • Robert L Sainburg, Phd, OTR · Penn State University

  • Carolee J Winstein, PhD,PT · University of Southern California

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-02
Primary Completion
2024-02-22
Completion
2024-08-05

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03634397 on ClinicalTrials.gov