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Sensory Evaluation of the Taste of Pediatric Medicines

NCT03627351 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 154

Last updated 2024-03-04

No results posted yet for this study

Summary

The investigators will conduct a systematic study of the sensory perception of a diverse set of commonly used pediatric liquid medications and excipients in tandem with an equally complete genetic analysis of the adult sensory panelists to investigate the relationship between genetic variation and individual differences in the perceived flavor (taste, smell, irritation) of pediatric medicines. The flavor of each medicine and excipient will be measured individually using both cognitively demanding methods unsuitable for young children and simpler measures validated for use by children. Salivary DNA samples will be collected to carry out genome wide association study (GWAS).

Conditions

  • Healthy

Sponsors & Collaborators

  • National Institute on Deafness and Other Communication Disorders (NIDCD)

    collaborator NIH

  • Children's Hospital of Philadelphia

    collaborator OTHER

  • Monell Chemical Senses Center

    lead OTHER

Principal Investigators

  • Julie A. Mennella, PhD · Monell Chemical Senses Center

  • Elizabeth Lowenthal, MD · Children's Hospital of Philadelphia

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2021-07-16
Completion
2024-03-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03627351 on ClinicalTrials.gov