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Modified HEART as Rule Out for Suspected ACS

NCT03619733 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1100

Last updated 2018-08-08

No results posted yet for this study

Summary

Validation of modified HEART score as a rule-out criterion for MACE at 6 weeks: a 2 centre prospective observational cohort with a direct comparison to TIMI, GRACE and high sensitive troponin T at limits of detection

Detailed description:

The HEART score, as defined previously by Backus et al1, is a risk score specifically developed for acute chest pain/ suspected acute coronary syndrome. The conventional scoring system for the troponin component of HEART is as follows: Troponin \<99th percentile =0 (in the case of Hstn T \[Roche} 14ng/l, 99th percentile up to X3 URL (99th percentile)= 1 (HSTN T =14-42ng/L, \>x3 URN =2 (HSTN T \>42ng/l).

We have previously defined that the optimal rule-out strategy for suspected acute coronary syndromes may well be a modified HEART score in a single centre study. This study is to prospectively validate the use of this score in a prospective unselected cohort of patients with possible acute coronary syndrome at 2 large secondary care centres

Conditions

Interventions

OTHER

no intervention

this is an observational study. no intervention is planned

Sponsors & Collaborators

  • Royal Liverpool University Hospital

    collaborator OTHER_GOV

  • University of Liverpool

    collaborator OTHER

  • Liverpool University Hospitals NHS Foundation Trust

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-06-01
Primary Completion
2018-09-01
Completion
2018-12-01

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03619733 on ClinicalTrials.gov