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Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes

NCT03612960 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2024-08-20

Study results available
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Summary

The overall goal of this study is to determine if switching to very low nicotine content cigarettes changes the function of brain circuitry involved in incentive salience and executive control among dependent smokers.

Conditions

  • Tobacco Dependence

Interventions

DRUG

Very low nicotine content cigarettes

Very low nicotine content cigarettes

DRUG

Normal nicotine content cigarettes

Normal nicotine content cigarettes

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • Milton S. Hershey Medical Center

    lead OTHER

Principal Investigators

  • Andrea Hobkirk, PhD · Milton S. Hershey Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-20
Primary Completion
2023-06-23
Completion
2023-06-23

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03612960 on ClinicalTrials.gov