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Hygiene and Bucco-dental Status of Patients With Oral Streptococcal Endocarditis

NCT03612245 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 403

Last updated 2018-08-02

No results posted yet for this study

Summary

Infective endocarditis (IE) is a rare (30 cases / million / year in France) and serious disease (20 % of deaths during hospitalization and 40 % after 5 years). The development of an IE results from the meeting between a bacteremia and a pre-existent heart disorder, most of the time valvular, allowing the transplant of the circulating bacteria and their multiplication in the endocardium. Recommendations of prophylactic antibiotic treatment have been established since 1954 for some medical, particularly dental procedures, at the origin of bacteremia. But this policy has recently been questioned because its efficacy has not been demonstrated.

The purpose of this study is identify the situations with risk, by comparing the oral health status and the hygiene of patients having an IE with oral streptococci to those in patients having an IE with microorganisms not of oral origin.

Conditions

  • Infective Endocarditis

Sponsors & Collaborators

  • Bichat Hospital

    collaborator OTHER

  • Central Hospital, Nancy, France

    collaborator OTHER

  • CHU de Reims

    collaborator OTHER

  • Pitié-Salpêtrière Hospital

    collaborator OTHER

  • Rennes University Hospital

    collaborator OTHER

  • Centre Hospitalier Universitaire de Besancon

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-05-01
Primary Completion
2012-07-01
Completion
2012-07-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03612245 on ClinicalTrials.gov