MedTrace Logo

Thyroid Dysfunction in Female Patients With Acne Vulgaris: [ Relation to Other Variables ]

NCT03602534 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 79

Last updated 2018-07-31

No results posted yet for this study

Summary

Acne is a chronic inflammatory disease of the pilo-sebaceous unit with a multi-factorial etiology. It is one of the most frequent cutaneous diseases, affecting more than eighty percent of the population at some point in their lives .

Endocrine factors especially androgens and steroids are one of multiple factors provoked to be involved in pathogenesis of acne . Thyroid hormones have steroid like action that have many regulatory functions in many body organ functions including skin and pilosebaceous unit. Furthermore, subtle thyroid dysfunction was shown to have a role in many disease conditions.

Thyroid hormone action on sebaceous glands is unclear. In hypothyroid states, sebocytes exhibit reduced rates of secretion that increases with thyroxine administration .

Conditions

  • Acne Vulgaris
  • Thyroid Dysfunction

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Emad Taha · Assiut University

Eligibility

Min Age
16 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-12-31
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03602534 on ClinicalTrials.gov