Gut and Intratumoral Microbiome Effect on the Neoadjuvant Chemotherapy-induced Immunosurveillance in Triple Negative Breast Cancer
NCT03586297 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 49
Last updated 2026-03-27
Summary
The probability of pCR in TNBC patients receiving standard of care neoadjuvant chemotherapy treatment is associated with the dominance of specific intestinal and intratumoral microbiota that promote anti-tumor immunosurveillance.
Conditions
Sponsors & Collaborators
-
Breast Cancer Research Foundation
collaborator OTHER -
Hackensack Meridian Health
lead OTHER
Principal Investigators
-
Marson Davidson, MD · Hackensack Meridian Health
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-08-27
- Primary Completion
- 2025-09-15
- Completion
- 2025-09-15
Countries
- United States
Study Locations
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