Gut and Intratumoral Microbiome Effect on the Neoadjuvant Chemotherapy-induced Immunosurveillance in Triple Negative Breast Cancer

NCT03586297 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 49

Last updated 2026-03-27

No results posted yet for this study

Summary

The probability of pCR in TNBC patients receiving standard of care neoadjuvant chemotherapy treatment is associated with the dominance of specific intestinal and intratumoral microbiota that promote anti-tumor immunosurveillance.

Conditions

Sponsors & Collaborators

  • Breast Cancer Research Foundation

    collaborator OTHER
  • Hackensack Meridian Health

    lead OTHER

Principal Investigators

  • Marson Davidson, MD · Hackensack Meridian Health

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-08-27
Primary Completion
2025-09-15
Completion
2025-09-15

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03586297 on ClinicalTrials.gov