Microparticles's Role in the Pathophysiology of Systemic Lupus Erythematosus and Systemic Sclerosis
NCT03575156 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 208
Last updated 2026-05-14
Summary
Our study aims at defining the role of circulating microparticles in the physiopathology of two rare auto-immune diseases: systemic lupus erythematosus (SLE) and systemic scleroderma (SSc). Microparticles might have an prognostic and diagnostic interest as well as potential for the discovery of new therapeutic strategies.
Conditions
- Systemic Lupus Erythematosus
- Systemic Scleroderma
Interventions
- BIOLOGICAL
-
blood sample
36 ml whole blood for Peripheral blood mononuclear cell (PBMC) and monocytes isolation
- BIOLOGICAL
-
urine sample
6 ml
Sponsors & Collaborators
-
University Hospital, Bordeaux
lead OTHER
Principal Investigators
-
Christophe RICHEZ, Prof · University Hospital, Bordeaux
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-09-20
- Primary Completion
- 2021-09-14
- Completion
- 2021-09-14
Countries
- France
Study Locations
More Related Trials
-
A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus
NCT02725515 ·Status: COMPLETED ·Phase: PHASE2
-
PRediction Of Flares In Lupus With autoantibodiEs and Chemokines
NCT04951427 ·Status: UNKNOWN
-
Study to Evaluate the Safety, Tolerability and Short Term Efficacy of Extracorporeal Specific Immunoadsorption LupusorbTM Columns for the Treatment of Systemic Lupus Erythematosus (SLE) Patients
NCT00608127 ·Status: UNKNOWN ·Phase: NA
-
Ferroptosis Role in the Pathophysiology of Systemic Lupus Erythematosus
NCT07260942 ·Status: RECRUITING ·Phase: NA
-
ROLE of PLATELETS in the PATHOPHYSIOLOGY of SYSTEMIC LUPUS
NCT06593041 ·Status: RECRUITING
-
Scrutinizing the Heterogeneity of SLE: Defining Phenotypes
NCT03348774 ·Status: UNKNOWN
-
Anti-nucleosome B Lymphocytes in Lupus
NCT01889654 ·Status: TERMINATED
-
LUMIER² Study : LUpus Molecular Immunomonitoring to Evaluate the Risk of Relapse
NCT02811094 ·Status: TERMINATED ·Phase: NA
-
Study of Systemic Lupus Erythematosus
NCT00001372 ·Status: RECRUITING
-
Mesenchymal Stromal Cells (MSC´s) in Renal Lupus
NCT03917797 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
NCT06015737 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
O-GlcNAcylation Role in the Pathophysiology of Systemic Lupus Erythematosus
NCT04440566 ·Status: COMPLETED ·Phase: NA
-
A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
NCT07175285 ·Status: RECRUITING
-
An Open Label Study to Evaluate Daratumumab in Participants With Moderate to Severe Systemic Lupus Erythematosus
NCT04810754 ·Status: UNKNOWN ·Phase: PHASE2
-
A Non-drug Study Profiling Cutaneous Lupus
NCT01923415 ·Status: COMPLETED
-
A Study to Continue the Administration of Deucravacitinib in Participants With Systemic Lupus Erythematosus (SLE) or Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) Who Have Completed Study IM011074 or Study IM011132
NCT06875960 ·Status: RECRUITING ·Phase: PHASE4
-
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
NCT06617325 ·Status: RECRUITING ·Phase: PHASE3
-
Study of Leukocyte Populations in Patients With Chronic Inflammatory
NCT04749875 ·Status: NOT_YET_RECRUITING
-
Anti-ficolin-3 Antibodies in Lupus Nephritis
NCT03842787 ·Status: COMPLETED
-
ILT-101 in Patients With Active Moderate to Severe Systemic Lupus Erythematosus (SLE)
NCT02955615 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)
NCT04857034 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
An Investigational Study to Evaluate BMS-986165 in Participants With Systemic Lupus Erythematosus
NCT03252587 ·Status: COMPLETED ·Phase: PHASE2
-
Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases:
NCT02890121 ·Status: COMPLETED
-
Myeloid Derived Suppressor Cells in Systemic Lupus Erythematosus
NCT05424627 ·Status: NOT_YET_RECRUITING
-
Prognostic Factors for Fatigue in Patients With Systemic Lupus Erythematosus
NCT07123220 ·Status: COMPLETED