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2-HOBA: Multiple Dosing Study in Healthy Humans

NCT03555682 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2019-08-13

No results posted yet for this study

Summary

The purpose of this study is to test how well people tolerate a new dietary ingredient called 2-HOBA and how it is metabolized in the body. 2-HOBA is a compound that occurs naturally in buckwheat seeds. This dietary ingredient has been used in animal studies, and single doses have been tolerated well when given to a small group of healthy people. In this study we will test how well people tolerate taking 2-HOBA over 2 weeks and how it is metabolized by the body.

Conditions

  • Healthy Volunteers

Interventions

DIETARY_SUPPLEMENT

2-HOBA

2-HOBA is a compound found in buckwheat and is given as 2-HOBA acetate

DIETARY_SUPPLEMENT

Placebo

Placebo Comparator

Sponsors & Collaborators

  • Vanderbilt University

    collaborator OTHER

  • National Institute on Aging (NIA)

    collaborator NIH

  • Metabolic Technologies Inc.

    lead INDUSTRY

Principal Investigators

  • John A Rathmacher, PhD · Metabolic Technologies Inc.

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
59 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-05-23
Primary Completion
2019-05-10
Completion
2019-05-10

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03555682 on ClinicalTrials.gov