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Oxidative Stress, Inflammation, and Lipoprotein in Metabolic Syndrome

NCT03553381 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2018-06-12

No results posted yet for this study

Summary

Obesity is associated with general low grade inflammation and, consequently, of oxidative stress that affects properties and functionality of lipoproteins. Metabolic syndrome exacerbate low grade inflammation. The intentional weight loss of at least 5% of the initial weight can modulate the pro-inflammatory state and reduce the oxidative stress related to the metabolic syndrome, thus diminishing the cardiovascular risk.

Conditions

  • Metabolic Syndrome
  • Obesity, Metabolically Benign

Interventions

OTHER

hypocaloric balanced diet

Sponsors & Collaborators

  • Luigi Sacco University Hospital

    collaborator OTHER

  • Istituti Clinici di Perfezionamento di Milano

    collaborator OTHER

  • roberta cazzola

    lead OTHER

Principal Investigators

  • Roberta Cazzola, PhD · University of Milan

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-12-30
Primary Completion
2012-04-30
Completion
2018-04-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03553381 on ClinicalTrials.gov