Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis
NCT03553095 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 92
Last updated 2025-12-12
Summary
This study will evaluate whether use of antidepressants can reduce gingival inflammation in patients with periodontal (gum) disease.
Conditions
- Chronic Periodontitis
- Depression
Interventions
- PROCEDURE
-
Periodontal Surgery
Samples will be collected from patient in need of periodontal therapy (surgical procedures i.e. gum surgery, tooth extraction and or dental implant surgery). As standard during this procedures remnant tissue is otherwise discarded.
Sponsors & Collaborators
-
University of Alabama at Birmingham
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-07-12
- Primary Completion
- 2019-12-30
- Completion
- 2026-12-30
Countries
- United States
Study Locations
More Related Trials
-
The Investigation of the Depression in Osteoarthritis
NCT02924662 ·Status: UNKNOWN
-
Model-based Defining of Subtypes of Depression and Optimal Treatment: an Integrated Techniques Module.
NCT04518592 ·Status: RECRUITING
-
Lifestyle Medicine for Depression
NCT03720145 ·Status: UNKNOWN ·Phase: NA
-
Peripheral Immunomarker Validation in Treatment-resistant Depression
NCT02752178 ·Status: COMPLETED
-
Developing a Self-Management Program for People With Depression and Chronic Medical Illness
NCT00523029 ·Status: COMPLETED ·Phase: NA
-
Lifestyle Interventions to Prevent Cognitive Deficits in Subjects With Depressive Symptoms: From Mechanisms to Clinical Practice
NCT07009223 ·Status: RECRUITING ·Phase: NA
-
Major Depression and Inflammatory Risk Markers for Coronary Heart Disease
NCT00037505 ·Status: COMPLETED
-
Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab
NCT06136546 ·Status: RECRUITING ·Phase: PHASE2
-
Effect of Short-Term Mindfulness-Based Training For Major Depression Disorder: An Eye-Tracking Study
NCT04071886 ·Status: UNKNOWN ·Phase: NA
-
Fluoxetine Mitigation Mental Health Study for Patients With Musculoskeletal Trauma
NCT04850222 ·Status: COMPLETED ·Phase: PHASE2
-
Post-Acute COVID-19, Inflammation, and Depression
NCT05346120 ·Status: WITHDRAWN ·Phase: PHASE2
-
Phenotype Depression Study
NCT01426997 ·Status: COMPLETED
-
Incidence of Metabolic Syndrome and Thyroid Dysfunction in Patients With Major Depressive Disorder
NCT01682785 ·Status: UNKNOWN
-
Gut Microbiota in Major Depressive Disorders With and Without Rapid Eye Movement Behavior Disorder
NCT05008120 ·Status: UNKNOWN
-
Lifestyle Medicine for Depression 2019
NCT04070417 ·Status: UNKNOWN ·Phase: NA
-
Multi-factor Model Constraction for Early Warning and Diagnosis of MDD
NCT05529576 ·Status: UNKNOWN ·Phase: PHASE4
-
Poststroke Depression of Clinical Trial Registration
NCT03863951 ·Status: UNKNOWN
-
Clinical Study on the Safety and Efficacy of Dental Pulp Mesenchymal Cells in the Treatment of Depression
NCT05127369 ·Status: UNKNOWN ·Phase: NA
-
The Effects of Exercise on Gut Bacteria, Mood and Cognition in Depression
NCT06398496 ·Status: RECRUITING ·Phase: NA
-
Validation of the Chinese Version of Oxford Depression Questionnaire
NCT05535270 ·Status: COMPLETED
-
Chronobiology and Depression: Circadian Analytics as a Biomarker for Depressive Subtypes
NCT03538275 ·Status: COMPLETED
-
Sevoflurane for Treatment-Resistant Depression
NCT05008939 ·Status: UNKNOWN ·Phase: NA
-
Exploratory Study on the Mood and Cytokine Levels in Female Healthy Participants and Major Depressive Disorder Patients
NCT01533285 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Identifying and Treating Depression in the Orthopaedic Trauma Population
NCT05976347 ·Status: RECRUITING ·Phase: PHASE4
-
Exploring Clinical Study Experiences of People With Depression
NCT05937932 ·Status: NOT_YET_RECRUITING