Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
NCT03551951 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 320
Last updated 2025-10-08
Summary
Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery. Also, early detection of lung cancer with low dose CT screening may cure patients at an early stage. Circulating and disseminated tumor cell (CTC/DTC) and circulating cell-free (cf) DNA isolation from the blood, urine and bone marrow will increase understanding of cancer spread and advance knowledge to develop individualized therapies and improve screening.
Conditions
- Non Small Cell Lung Cancer
- Esophageal Cancer
- Gastric Cancer
- Pancreatic Cancer
- Hepatocellular Cancer
- Colorectal Cancer
Interventions
- DIAGNOSTIC_TEST
-
Test for circulating tumor cells, DNA alterations
Sponsors & Collaborators
-
Harry S. Truman Memorial Veterans' Hospital
collaborator FED -
University of Missouri-Columbia
lead OTHER
Principal Investigators
-
Jussuf T Kaifi, MD · University of Missouri Health Care
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-07-01
- Primary Completion
- 2027-12-30
- Completion
- 2027-12-30
Countries
- United States
Study Locations
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