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Early Biomarkers for ARthritic PAIN to Guide Improved Treatments for Arthritis

NCT03533569 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2020-10-27

No results posted yet for this study

Summary

Osteoarthritis (OA) is a condition affecting the whole joint and is a major cause of pain and disability worldwide. Although OA is very common, the initial steps which lead to the development of pain and tissue damage are not fully understood. In this study participants will be investigated for markers in the blood, joint and urine in people who have a diagnosis of osteoarthritis or inflammatory arthritis and are receiving a steroid injection for their condition. Markers will be evaluated in participants with osteoarthritis compared with other types of arthritis, including rheumatoid arthritis and spondyloarthritis.

Conditions

Interventions

PROCEDURE

Intra-articular corticosteroid injection

Participants with arthritis will undergo usual care with knee synovial fluid aspiration followed by intra-articular corticosteroid injection

Sponsors & Collaborators

  • Wellcome Trust

    collaborator OTHER

  • Rosetrees Trust

    collaborator OTHER

  • St George's, University of London

    lead OTHER

Principal Investigators

  • Nidhi Dr Sofat, MD, PhD · St George's, University of London

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-04-02
Primary Completion
2021-04-02
Completion
2022-04-02

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03533569 on ClinicalTrials.gov