Pembrolizumab in Untreated B-Cell Non-Hodgkin Lymphoproliferative Diseases
NCT03498612 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 9
Last updated 2025-11-12
Summary
This phase II trial studies how well pembrolizumab works in treating patients with B-cell non-Hodgkin lymphoproliferative diseases that have not been treated. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Conditions
- Follicular Lymphoma
- Indolent B-Cell Non-Hodgkin Lymphoma
- Marginal Zone Lymphoma
Interventions
- OTHER
-
Laboratory Biomarker Analysis
Correlative studies
- BIOLOGICAL
-
Given IV
Sponsors & Collaborators
- collaborator INDUSTRY
- lead OTHER
Principal Investigators
-
Ajay K. Gopal · Fred Hutch/University of Washington Cancer Consortium
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-07-09
- Primary Completion
- 2021-06-09
- Completion
- 2024-08-29
- FDA Drug
- Yes
Countries
- United States
Study Locations
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