Fludarabine and Rituximab for the Treatment of Marginal Zone Non-Hodgkin's Lymphoma
NCT00117156 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 26
Last updated 2016-08-01
Summary
The purpose of this study is to determine the effectiveness of six cycles of concurrent fludarabine and rituximab in patients with mucosa-associated lymphoid tissue (MALT) lymphoma, marginal zone lymphoma (MZL) or CD5-, CD10-, CD20+ low-grade B cell lymphomas.
Conditions
- Lymphoma, Non-Hodgkin
- MALT Lymphoma
Interventions
- DRUG
- DRUG
Sponsors & Collaborators
-
Beth Israel Deaconess Medical Center
collaborator OTHER -
Massachusetts General Hospital
collaborator OTHER -
University of Rochester
collaborator OTHER -
Genentech, Inc.
collaborator INDUSTRY - collaborator INDUSTRY
- lead OTHER
Principal Investigators
-
Jennifer R. Brown, MD, PhD · Dana-Farber Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-12-31
- Primary Completion
- 2008-10-31
- Completion
- 2012-01-31
Countries
- United States
Study Locations
More Related Trials
-
Epco, Zanu, Ritux for R/R FL or MZL
NCT06563596 ·Status: RECRUITING ·Phase: PHASE2
-
Alvocidib, Fludarabine Phosphate, and Rituximab in Treating Patients With Lymphoproliferative Disorders or Mantle Cell Lymphoma
NCT00058227 ·Status: COMPLETED ·Phase: PHASE1
-
Rituximab in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease
NCT00003849 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Ibrutinib With Rituximab in People With Untreated Marginal Zone Lymphoma
NCT04212013 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas
NCT06350318 ·Status: RECRUITING ·Phase: PHASE2
-
Combination of Oral Fludarabine, Mitoxantrone Und Rituximab Induction Therapy and Rituximab Maintenance Therapy in Follicular B-Cell Lymphoma
NCT01560117 ·Status: COMPLETED ·Phase: PHASE2
-
Radiolabeled Monoclonal Antibody Plus Rituximab With and Without Filgrastim and Interleukin-11 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
NCT00012298 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Phase II Study of Chlorambucil and Subcutaneous Rituximab in Patients With Extranodal MALT Lymphoma
NCT01808599 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Ibrutinib in Combination With Rituximab and Lenalidomide in Treating Patients With Previously Untreated, Stage II-IV Follicular Lymphoma or Marginal Zone Lymphoma
NCT02532257 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Induction and Maintenance Treatment With MabThera (Rituximab) in Patients With Indolent B-Cell Nonfollicular Lymphomas
NCT01153971 ·Status: COMPLETED ·Phase: PHASE2
-
Fludarabine and Monoclonal Antibody Therapy in Treating Patients With Untreated B-cell Chronic Lymphocytic Leukemia
NCT00003248 ·Status: COMPLETED ·Phase: PHASE2
-
MG4101 Plus Rituximab Including Lymphodepletion in Patient With r/r NHL B-cell Origin
NCT03778619 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Phase III, Multicentre, Randomised Study of Fludarabine/Cyclophosphamide Combination With or Without Rituximab in Patients With Untreated Mantle Cell Lymphoma
NCT00641095 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
NCT05100862 ·Status: RECRUITING ·Phase: PHASE3
-
Rituximab Plus Interleukin-2 in Treating Patients With Hematologic Cancer
NCT00010192 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety Study of SH T 586 in Combination With Rituximab to Treat Low-Grade NHL
NCT00311129 ·Status: COMPLETED ·Phase: PHASE2
-
Study Evaluating the Effect of R-mabHDI in Lymphocytic Predominant Hodgkin's Lymphoma
NCT00816959 ·Status: UNKNOWN ·Phase: PHASE3
-
Rituximab, Fludarabine, Mitoxantrone, Dexamethasone (R-FND) Plus Zevalin for High-Risk Follicular Lymphoma
NCT00290511 ·Status: COMPLETED ·Phase: PHASE2
-
Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy
NCT06834373 ·Status: RECRUITING ·Phase: PHASE2
-
Glofit and Obin in Follicular Lymphoma and Marginal Zone Lymphoma
NCT05783596 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Ibrutinib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Older Patients With Newly Diagnosed Mantle Cell Lymphoma
NCT01880567 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of MabThera/Rituxan (Rituximab) in Patients With Follicular Non-Hodgkin's Lymphoma
NCT01388959 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma
NCT00867529 ·Status: COMPLETED ·Phase: PHASE2
-
Study Evaluating Inotuzumab Ozogamicin [CMC-544] Administered In Combination With Rituximab In Subjects With Non-Hodgkin's Lymphoma (NHL)
NCT00299494 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase II Study to Evaluate the Efficacy and Safety of F520 Combined With F007 in Patients With RR DLBCL
NCT05178836 ·Status: UNKNOWN ·Phase: PHASE2