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Novel BIochemical Markers for Predicting Type 2 NEurological Complications of Surgical Coronary Revascularization (BINER)

NCT03493256 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2020-02-05

No results posted yet for this study

Summary

In this single center prospective cohort study a total of 100 patients scheduled for elective off-pump CABG will be recruited. They will be allocated to one study and one control group according to the presence or absence of postoperative type 2 neurological complications. The two groups will be compared in terms of serum concentrations of glial fibrillary acidic protein (GFAP), neuroserpin (NSP), phosphorylated axonal neurofilament subunit H (pNfH) and visinin-like protein 1 (VILIP-1) at the time of skin incision and closure as well as 24 hours and 7 days following surgery. Diagnostic performance of these markers for predicting type 2 neurological complications of off-pump CABG will be assessed.

Conditions

  • Neurological Complication of Procedure (Disorder)

Interventions

OTHER

exposure to type 2 neurological complications

exposure to postoperative cognitive dysfunction (POCD) or postoperative delirium (POD), or both concurrently.

Sponsors & Collaborators

  • Collegium Medicum w Bydgoszczy

    lead OTHER

Principal Investigators

  • Krzysztof Szwed, Dr · Department of Clinical Neuropsychology, Nicolaus Copernicus University, Collegium Medicum.

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-04-01
Primary Completion
2019-03-01
Completion
2019-03-01

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03493256 on ClinicalTrials.gov