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Microglial Activation in Inflammatory Bowel Disease

NCT03487926 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2025-04-22

No results posted yet for this study

Summary

The purpose of this study is to monitor microglial activation in participants with inflammatory bowel disease (IBD) and investigate the relationship that exists between these patients and their risk of acquiring major depressive episodes (MDE). Patients with both IBD and MDE will be subsequently approached to participate in the study.

Conditions

  • Major Depressive Episode
  • Inflammatory Bowel Diseases

Interventions

RADIATION

[18F]FEPPA

up to 3 PET Scans (\[18F\]FEPPA PET scans done 3 to 6 months apart, and one \[11C\]SL2511.88 PET scan) and 1 MRI

Sponsors & Collaborators

Principal Investigators

  • Jeffrey H Meyer, M.D.,PhD · Research Imaging Centre, Centre for Addiction and Mental Health

Eligibility

Min Age
19 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-09-14
Primary Completion
2024-11-19
Completion
2024-11-19

Countries

  • Canada

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03487926 on ClinicalTrials.gov