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Role of Interferon-λ and Vaccine Response

NCT03467074 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2019-10-17

No results posted yet for this study

Summary

The following observational study will investigate whether the vaccine response (antibodies, T and B cells) after allogeneic stem cell transplantation is influenced by genetic polymorphisms in the interferon lambda signal.

Conditions

  • Vaccine Response Impaired
  • Allogeneic Stem Cell Transplantation

Interventions

BIOLOGICAL

influenza A/B vaccine

Regardless of the study enrollment, a two-time influenza vaccination at the start of the flu season is recommended every 4 weeks for all patients after stem cell transplantation. The vaccine is a trivalent inactivated non-adjuvanted influenza virus vaccine containing two influenza A viruses: pandemic H1N1, and H3N2, and an influenza B virus

Sponsors & Collaborators

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Adrian Egli, PD MD · Department of Clinical Microbiology

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-09-01
Primary Completion
2017-08-31
Completion
2017-12-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03467074 on ClinicalTrials.gov