Pegcetacoplan (APL-2) in Neovascular AMD
NCT03465709 · Status: TERMINATED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 17
Last updated 2020-09-16
Summary
Safety Assessment of Pegcetacoplan in Patients with Neovascular AMD
Conditions
- Neovascular Age-related Macular Degeneration
Interventions
- DRUG
-
Pegcetacoplan
Study Drug
Sponsors & Collaborators
-
Apellis Pharmaceuticals, Inc.
lead INDUSTRY
Principal Investigators
-
Federico Grossi, MD, PhD · Apellis Pharmaceuticals, Inc.
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-02-14
- Primary Completion
- 2019-04-05
- Completion
- 2019-04-05
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration
NCT03525600 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate the Safety of Intravitreal APL-2 in Patients Diagnosed With Geographic Atrophy
NCT03777332 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II/III Study of Anti-VEGF in Neovascular AMD
NCT00021736 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Safety and Pharmacokinetics of Abicipar Pegol Intravitreal Injections in Patients With Neovascular AMD
NCT02859766 ·Status: COMPLETED ·Phase: PHASE1
-
Intravitreous Pegaptanib Sodium Injection in Patients With Exudative Age-Related Macular Degeneration (AMD)
NCT00088192 ·Status: COMPLETED ·Phase: NA
-
A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration
NCT06161584 ·Status: ACTIVE_NOT_RECRUITING
-
X-82 to Treat Age-related Macular Degeneration
NCT02348359 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
NCT06779773 ·Status: RECRUITING
-
Study of the Safety, Tolerability and Pharmacokinetics of 1 Mg/Eye and 3 Mg/Eye Pegaptanib Sodium in Patients With Exudative Age-Related Macular Degeneration (AMD)
NCT00215670 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
RGX-314 Gene Therapy Pharmacodynamic Study for Neovascular Age-related Macular Degeneration (nAMD)
NCT04832724 ·Status: COMPLETED ·Phase: PHASE2
-
Study of AdGVPEDF.11D in Neovascular Age-related Macular Degeneration (AMD)
NCT00109499 ·Status: COMPLETED ·Phase: PHASE1
-
On-label tReatment With Intravitreal Aflibercept injectiOn for Patients With Persistent Pigment epitheliaL Detachments in Neovascular Age Related Macular Degeneration (AMD)
NCT01670162 ·Status: UNKNOWN ·Phase: PHASE4
-
To Describe the Use of Intravitreal Aflibercept and to Describe Follow-up as Well as Treatment Patterns in Patients With Wet Age-related Macular Degeneration (wAMD) or Diabetic Macular Edema (DME) in Routine Clinical Practice in Canada.
NCT02540369 ·Status: COMPLETED
-
A Study to Evaluate Pazopanib Tablets in Patients Who Have Neovascular Age-related Macular Degeneration
NCT01154062 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Safety, Tolerability and Effectiveness of MT-0814 for the Treatment of Age-related Macular Degeneration
NCT03869684 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate Abicipar Pegol for Safety and Treatment Effect in Participants With Neovascular Age-related Macular Degeneration (AMD)
NCT03539549 ·Status: COMPLETED ·Phase: PHASE2
-
12 Week Patient Study in Neovascular Age-related Macular Degeneration (AMD)
NCT01362348 ·Status: TERMINATED ·Phase: PHASE2
-
A Clinical Trial to Explore Safety and Efficacy of Different Doses of Pegaptanib Sodium, Compared to Sham, in Patients With Wet AMD.
NCT00321997 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD
NCT05407636 ·Status: RECRUITING ·Phase: PHASE3
-
A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration
NCT07029945 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Study to Evaluate a Pegcetacoplan (Syfovre®) Prefilled Syringe
NCT07214740 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Tolerability of Intravenous LFG316 in Wet Age-related Macular Degeneration (AMD).
NCT01624636 ·Status: TERMINATED ·Phase: PHASE2
-
Anti-VEGF Therapy for Subfoveal Hemorrhage in Patients With Neovascular Age-Related Macular Degeneration
NCT03699618 ·Status: TERMINATED
-
Short-term Clinical Effects of Intravitreal Aflibercept Injection 2.0mg as a Predictor of Long-term Results
NCT01657669 ·Status: UNKNOWN ·Phase: PHASE4
-
Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-Related Macular Degeneration (AMD)
NCT02418754 ·Status: TERMINATED ·Phase: PHASE2