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Interaction of Melatonin With MTNR1B Genotype on Glucose Control - Study 2

NCT03464084 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2022-07-26

No results posted yet for this study

Summary

This project aims to test the impact of melatonin and MTNR1B variation on regulation glucose regulation in a highly controlled in-laboratory setting and ex vivo in pancreatic islets.

Conditions

  • Glucose
  • Circadian Rhythm
  • Melatonin
  • Genes
  • Light

Interventions

DRUG

placebo

Capsules containing microcrystalline cellulose

DIETARY_SUPPLEMENT

melatonin

5 mg of melatonin per os.

OTHER

bright light

room light will be bright

OTHER

dim light

room light will be dim

Sponsors & Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    collaborator NIH

  • Brigham and Women's Hospital

    lead OTHER

Principal Investigators

  • Frank AJL Scheer, PhD · Brigham and Women's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-02-17
Primary Completion
2022-07-19
Completion
2022-07-19

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03464084 on ClinicalTrials.gov