MedTrace Logo

Soft Peri-implant Tissue Around Different Abutment Materials

NCT03459547 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2021-09-28

No results posted yet for this study

Summary

Soft tissue attachment to the implant surface serves as a biological seal preventing the development of inflammatory periimplant diseases (i.e. peri-implant mucositis and peri-implantitis).It occurs in the presence of a biomaterial during healing of the surgical wound that might be influence by this foreign body. Myofibroblasts represent key players in the physiological reconstruction of connective tissue after injury.

This work will focus on the role of myofibroblasts during the early phases of the healing process in peri-implant tissues around four different abutment materials.

Conditions

  • Dental Implant Failure Nos
  • Wound Heal

Interventions

DEVICE

dental implant

Local anesthesia, flap preparation, dental implant insertion, flap suture, healing abutment insertion. Peri-implant soft tissue samples taken prior to implant placement and 24 hours after.

Sponsors & Collaborators

  • Max-Planck Institute of Molecular Cell Biology and Genetics

    collaborator OTHER

  • University of Roma La Sapienza

    lead OTHER

Principal Investigators

  • Andrea Pilloni, MD DDS Ms · University of Roma La Sapienza

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-06
Primary Completion
2021-12-31
Completion
2021-12-31

Countries

  • Italy

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03459547 on ClinicalTrials.gov