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Physical Impairments in Allogeneic-HSCT

NCT03448627 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 122

Last updated 2019-04-16

No results posted yet for this study

Summary

Pulmonary functions, exercise capacity and muscle strength deteriorate in survived hematopoietic stem cell transplantation (HSCT) recipients due to toxic effects of chemotherapy, radiotherapy, conditioning regimens and/or corticosteroid use before HSCT, prolonged stay of recipients in rooms with laminar airflow and strict infection control rules during process of HSCT. There are also limited numbers of studies demonstrated pulmonary function abnormalities, decreased maximal exercise capacity, respiratory and peripheral muscle weakness in recipients. Current study was planned since no study compared pulmonary functions, maximal exercise capacity, respiratory and peripheral muscle strength between recipients and healthy individuals in the literature.

Conditions

  • Stem Cell Transplantation

Sponsors & Collaborators

  • Gazi University

    lead OTHER

Principal Investigators

  • Gülşah Barğı, PhD · Gazi University

  • Meral Boşnak Güçlü, PhD · Gazi University

  • Gülsan Türköz Sucak · Bahçeşehir University

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-03-31
Primary Completion
2014-11-30
Completion
2017-12-31

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03448627 on ClinicalTrials.gov