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Grasping Function After Spinal Cord Injury

NCT03447509 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-01-27

No results posted yet for this study

Summary

The overall goals of this proposal are to examine the contribution of physiological pathways to the control of grasping behaviors after cervical SCI, and to maximize the recovery of grasping by using tailored non-invasive brain stimulation and acoustic startle protocols with motor training. The investigators propose to study two basic grasping behaviors, which are largely used in most daily-life activities: a precision grip and a power grip.

Conditions

  • Spinal Cord Injury

Interventions

DEVICE

Sham iTMS

Sham or fake stimulation will be given to the brain in a non invasive manner.

OTHER

Training

The participant will be instructed to do repetitive motor movements with their arm or hand.

DEVICE

iTMS

Small magnetic pulse will be given to the brain in a non invasive manner.

OTHER

Motor Task

Participants will be asked to perform specific motor tasks or movements with their fingers, hands, and arms.

Sponsors & Collaborators

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Monica A Perez, PhD · Edward Hines Jr. VA Hospital, Hines, IL

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-03-17
Primary Completion
2025-06-30
Completion
2025-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03447509 on ClinicalTrials.gov