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Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia

NCT05157282 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 86

Last updated 2026-01-16

No results posted yet for this study

Summary

In support of the long-term goal of developing new strategies to increase limb function after SCI, the objectives of this proposal are to: 1) Examine the behavioral and physiological effects of TESS on upper-limb muscles after cervical SCI; and 2) Maximize the recovery of reaching and grasping potential by using tailored TESS in a task-specific manner with motor training. Veterans with cervical spinal injuries and healthy volunteers will be recruited for this study.

Conditions

  • Spinal Cord Injury

Interventions

DEVICE

TESS

Small stimulation pulses will be given to the spine at C5-6 in a non invasive manner.

OTHER

Training

The participant will be instructed to do repetitive motor movements with their arm or hand.

OTHER

Motor Task

Participants will be asked to perform specific motor tasks or movements with their fingers, hands, and arms.

DEVICE

sham-TESS

Small sham stimulation pulses will be given to the spine at C5-6 in a non invasive manner.

Sponsors & Collaborators

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Monica A Perez, PhD · Edward Hines Jr. VA Hospital, Hines, IL

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-25
Primary Completion
2027-01-29
Completion
2027-02-01
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05157282 on ClinicalTrials.gov