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Role of Endothelial Cells in the Pathogenesis of Chronic Urticaria.

NCT03443362 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2022-07-19

No results posted yet for this study

Summary

Chronic urticaria (CU) is a disease that usually affects a large visible amount of surface of the skin. It is accompanied by severe itch and feeling of burned skin. Therefore the disease has a big impact on the quality of life of patients. Unfortunately, to date CU is not easily controlled by its few existing treatment options (i.e. antihistamines, omalizumab, cyclosporine).

This research's main perspective is to improve quality of life for CU patients by first of all focusing on a good clinical diagnosis of (different subtypes of) CU in a CU reference center, and secondly by gaining more insight on the pathogenesis of the disease to expand knowledge on potential new targeted treatments for the patients.

Conditions

  • Chronic Urticaria

Interventions

PROCEDURE

Punch Biopsy

A 3 mm punch biopsy will be taken from lesional and non-lesional skin as a routine procedure.

PROCEDURE

Blood sampling

Blood sampling

Sponsors & Collaborators

  • Olivier Michel

    lead OTHER

Principal Investigators

  • Yora Mostmans, MD · CHU Brugmann

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-01
Primary Completion
2022-12-31
Completion
2022-12-31

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03443362 on ClinicalTrials.gov