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Cardiometabolic and Mental Health in the RGV

NCT03436875 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2023-05-10

No results posted yet for this study

Summary

Microvascular insulin resistance has been shown to precede myocyte insulin resistance and impairments in metabolic function. However, there is no convincing data showing the relationship between impaired microvascular flow and impaired metabolic flexibility. Recent evidence exists that impaired microvascular blood flow in Caucasians directly contributes to impaired metabolic flexibility in Caucasians (Diabetes Care), however there is no such evidence in Hispanics. Since there is a large disparity in cardiometabolic disease in Hispanics, this study aims to determine the role of impaired microvascular blood flow on impaired substrate oxidation switching (metabolic flexibility) in healthy people at risk for developing type 2 diabetes.

Conditions

  • Microvessels
  • Carbohydrate Metabolism
  • Diabetes Mellitus, Type 2

Sponsors & Collaborators

  • University of Texas Rio Grande Valley

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2028-12-30
Completion
2028-12-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03436875 on ClinicalTrials.gov