MedTrace Logo

Pre-adolescent Stress and Health Study

NCT03436706 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2018-04-30

No results posted yet for this study

Summary

Aim 1: To characterize allostatic load (AL) biomarkers in a sample of low-income early adolescents (N = 225). How many children living in low-income homes have atypical or out-of-range biomarker levels, on which biomarkers, and in what combinations (Aim 1a)? Do AL biomarker elevations predict physical and mental health problems in early adolescence (Aim 1b)? How much and what type of change in AL biomarkers occurs between ages 11 and 14 (Aim 1c)?

Aim 2: To investigate in the same sample of early adolescents exposed to varying levels of early life stress (ELS), the relative contributions made by ELS, recent (past year), and cumulative (since age 5) stress exposures to initial AL levels at T1 (Aim 2a), and to changes in AL across the two years of the study (Aim 2b).

Aim 3: To explore the extent to which coping resources, including children's coping skills, children's physiologic self-regulation, and parental coping socialization, uniquely and synergistically influence AL levels and accumulations in these early adolescents.

Conditions

  • Stress

Interventions

OTHER

exposure

exposure to chronic stress

Sponsors & Collaborators

  • University of Vermont

    collaborator OTHER

  • Milton S. Hershey Medical Center

    collaborator OTHER

  • Penn State University

    lead OTHER

Principal Investigators

  • Martha E Wadsworth, PhD · Penn State

Eligibility

Min Age
132 Months
Max Age
156 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-31
Primary Completion
2024-12-31
Completion
2024-12-31

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03436706 on ClinicalTrials.gov