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Assessment of Portal Hypertension With Multiparametric MRI

NCT03436550 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 69

Last updated 2023-03-06

No results posted yet for this study

Summary

The purpose of this study is to determine whether new multiparametric magnetic resonance imaging (MRI) methods (including diffusion-weighted MRI, dynamic contrast-enhanced MRI, MR elastography and phase-contrast imaging) can be useful in assessing liver damage and degree of portal hypertension (a complication of advanced liver fibrosis and cirrhosis) secondary to chronic liver disease, compared to ultrasound measurement of liver stiffness \[acoustic radiation force impulse (ARFI) ultrasound\] and routine blood tests. MRI uses magnetic fields to look at soft tissues in the body. This study will ultimately help to determine whether these methods will be useful in identifying liver disease and their complications that cannot be well-understood using current liver MRI techniques.

Conditions

  • Portal Hypertension
  • Clinically Significant Portal Hypertension

Interventions

PROCEDURE

mpMRI

Multiparametric MRI

PROCEDURE

ARFI US

Acoustic radiation force impulse is a type of ultrasound elastography

Sponsors & Collaborators

Principal Investigators

  • Bachir Taouli, MD · Icahn School of Medicine at Mount Sinai

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-03-20
Primary Completion
2022-07-19
Completion
2022-07-19

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03436550 on ClinicalTrials.gov