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Circulating Tumor Cells in Operative Blood

NCT02150746 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3

Last updated 2016-02-23

No results posted yet for this study

Summary

It is hypothesized that circulating tumor cells (CTCs) from pancreatic adenocarcinoma are released into the peritoneal cavity through blood lost during the surgical resection of these tumors resulting in peritoneal recurrence despite appropriate surgical resection. Targeting the mechanisms responsible for CTC adhesion to the peritoneum may result in inhibition of implantation and growth, thus preventing this mode of pancreatic cancer recurrence postoperatively.

Conditions

  • Carcinoma, Pancreatic Ductal

Interventions

PROCEDURE

Peripheral/Central Venous Blood Draw

Baseline sample of whole blood to be assessed for circulating tumor cells. Samples will be acquired via venipuncture unless a pre-existing central venous catheter is in place in which case the sample will be drawn from this.

PROCEDURE

Peritoneal Wash

Prior to the start of the surgical resection, irrigation of the abdominal cavity will be performed and collected to determine baseline pancreatic cancer cells that may be present in the abdominal cavity.

Sponsors & Collaborators

  • University of Florida

    lead OTHER

Principal Investigators

  • Ryan M Thomas, MD · University of Florida

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-02-28
Primary Completion
2016-02-29
Completion
2016-02-29

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02150746 on ClinicalTrials.gov