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The Effects of Tranexamic Acid on Blood Loss During Orthognathic Surgery

NCT03433144 · Status: WITHDRAWN · Phase: PHASE4 · Type: INTERVENTIONAL

Last updated 2021-08-06

No results posted yet for this study

Summary

This study seeks to answer the question: Does a single pre-operative dose of tranexamic acid have a statistically significant reduction in blood loss during orthognathic surgery?

If it does, this drug may begin to be used routinely during orthognathic surgery to reduce blood loss in our patients.

Conditions

  • Tranexamic Acid
  • Orthognathic Surgery

Interventions

DRUG

Tranexamic Acid Injectable Solution

the drug will be given to patients intravenously at a dose of 10mg/kg pre-operatively after induction on general anesthesia

OTHER

Placebo (normal saline 0.9%)

An equivalent amount of normal saline (0.9%) will be given to the patient pre-operatively after induction of general anesthesia. The amount of saline given will correspond to the same amount of fluid which would have been given had the patient been in the intervention group.

Sponsors & Collaborators

  • Nick Emanuele

    lead OTHER

Principal Investigators

  • Nick Emanuele, DDS, BBA · Nova Scotia Health Authority

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
16 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-06-01
Primary Completion
2019-02-01
Completion
2020-07-06

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03433144 on ClinicalTrials.gov