MedTrace Logo

Thoracic Paravertebral Blocks in Open Nephrectomy

NCT03428633 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2023-10-13

No results posted yet for this study

Summary

60 patients ASA I-III, undergoing open nephrectomy will be randomly assigned into one of two groups, namely group A (n=30), where a thoracic paravertebral block will be performed preoperatively and a paravertebral catheter for continuous and patient controlled bolus local anesthetic (ropivacaine) doses will be inserted and group B (n=30) where morphine IV will be administered at the beginning and the end of operation and postoperatively through patient controlled IV doses. NRS scores in static and dynamic conditions, complications, patient satisfaction, oxidative stress (through lactic acid, superoxide dismutase, malondialdehyde) and NGAL pre- and postoperatively, will be recorded.

Conditions

  • Nephrectomy
  • Analgesia

Interventions

DRUG

Ropivacaine

Paravertebral block using ropivacaine preoperatively and postoperatively

DRUG

Morphine

Morphine intraoperatively and postoperatively

Sponsors & Collaborators

  • Michail Tsagkaris

    collaborator UNKNOWN

  • Chryssoula Staikou

    collaborator UNKNOWN

  • Ioannis Karavokyros

    collaborator UNKNOWN

  • Asklepieion Voulas General Hospital

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
14 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-09
Primary Completion
2021-02-01
Completion
2023-02-01

Countries

  • Greece

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03428633 on ClinicalTrials.gov