Effect of Morning Versus Evening Perindopril on Blood Pressure Control in People With Type 2 Diabetes
NCT03393715 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2018-01-08
Summary
We assessed the influence of time of administration of ACE inhibitors on circadian blood pressure control in sub Saharan type 2 diabetes patients with stage 1 hypertension over 56 days as first line treatment.
Conditions
- Diabetes Mellitus, Type 2
- Hypertension
Interventions
- DRUG
-
Perindopril Oral Tablet
Perindopril oral tablet morning versus evening
Sponsors & Collaborators
-
University of Yaounde 1
collaborator OTHER -
Yaounde Central Hospital
lead OTHER_GOV
Principal Investigators
-
Eugène Sobngwi, MD, PhD · Yaounde Central Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-02-29
- Primary Completion
- 2016-07-31
- Completion
- 2016-08-31
More Related Trials
-
Sodium Glucose Cotransporter-2 Inhibitors and Salt-sensitivity in Type 2 Diabetes
NCT06007157 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Losartan and Perindopril in Blacks Type 2 Diabetics Patients
NCT04222686 ·Status: COMPLETED ·Phase: PHASE4
-
GLUcose Transport and REnalPROtection in Chronic Kidney Disease
NCT05998837 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Antihypertensive Medication Exposure as Risk for Impaired Glucose Tolerance: A PEAR Sub-Study
NCT01099397 ·Status: COMPLETED
-
Comparing the Renal Effect of Dipeptidyl-peptidase 4 Inhibitors and Sulfonylureas
NCT03983551 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Dapagliflozin on Nighttime Blood Pressure in Type 2 Diabetes
NCT03887416 ·Status: UNKNOWN ·Phase: PHASE4
-
Antidiuretic Function Before and During Treatment With SGLT2 Inhibitors
NCT03917758 ·Status: UNKNOWN ·Phase: NA
-
Maximal Dose of Angiotensin Converting Enzyme (ACE) Inhibitor for Treatment of Diabetic Kidney Disease
NCT00118976 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Blood Pressure Reduction, Safety, and Tolerability of Canagliflozin in Patients With Hypertension and Type 2 Diabetes Mellitus on Stable Doses of Anti-hyperglycemic and Anti-hypertensive Agents
NCT01939496 ·Status: COMPLETED ·Phase: PHASE4
-
Mechanistic Study of the Systolic Blood Pressure Lowering Effect of Dapagliflozin in Type 2 Diabetes
NCT02372955 ·Status: UNKNOWN ·Phase: PHASE4
-
Effects of Rosiglitazone on Renal Hemodynamics and Proteinuria of Type 2 Diabetic Patients With Renal Insufficiency Due to Overt Diabetic Nephropathy
NCT00324675 ·Status: COMPLETED ·Phase: NA
-
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes
NCT06983054 ·Status: RECRUITING ·Phase: PHASE4
-
DPP-4 Inhibitor and Serum BNP Level of Diabetic Patients With Congestive Heart Failure
NCT02312427 ·Status: COMPLETED ·Phase: PHASE4
-
A Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 Diabetes And Overt Nephropathy
NCT01200394 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of SGLT2 Inhibitor on Hemodynamic Parameters in Resistant Hypertensive Subjects
NCT03089333 ·Status: COMPLETED ·Phase: PHASE4
-
Dapagliflozin Delays the Loss of Renal Function in Peritoneal Dialysis Patients
NCT06398977 ·Status: RECRUITING ·Phase: NA
-
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study
NCT05727579 ·Status: COMPLETED ·Phase: PHASE4
-
Characterization of the Kinetics of Renal Glucose Reabsorption in Response to Dapagliflozin in Healthy Subjects and in Subjects With Type 2 Diabetes Mellitus (T2DM)
NCT01165268 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Novel Antidiabetic Drug Combined With Angiotensin Receptor/Neprilysin Inhibitor on Urinary Protein
NCT05922852 ·Status: UNKNOWN
-
A Study to Investigate the Effect of Food on Balcinrenone/Dapagliflozin Pharmacokinetics in Fed and Fasted State and Pharmacokinetics of Balcinrenone When Dosed With a P-gp Inhibitor in Healthy Participants.
NCT06979388 ·Status: COMPLETED ·Phase: PHASE1
-
Doxazosin Effects on ABPM in Hypertensive Patients With Diabetic Nephropathy
NCT00295555 ·Status: COMPLETED ·Phase: PHASE4
-
The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans
NCT03938389 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Empagliflozin and Sympathetic Nerve Traffic
NCT03254849 ·Status: COMPLETED ·Phase: PHASE4
-
PREVENTKD (Prevent Risks by Early interVEntion at Nighttime in Type 1 Diabetes for Kidney Disease)
NCT00729365 ·Status: TERMINATED ·Phase: PHASE3
-
Action in Diabetes and Vascular Disease Preterax and Diamicron MR Controlled Evaluation Post Trial Observational Study
NCT00949286 ·Status: COMPLETED