MedTrace Logo

Comparing Postoperative Pain Following COX-2 and Prostanoids Expression

NCT03391570 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2018-01-05

No results posted yet for this study

Summary

The purpose of this study is to compare postoperative pain following COX-2 and prostanoids expression in women who underwent laparoscopic surgery for female genital disease in order to evaluate the effect of COX-2 on local inflammation, COX-2 and prostanoids expression followed by exposure time to carbon dioxide(CO2) gas, and degree of postoperative pain.

Conditions

  • Female Genital Disease

Interventions

DRUG

COX-2 inhibitor

Celebrex 200mg/1cap 2 tablets, take medication an hour before surgery

DRUG

Placebo Oral Tablet

Ramnos 250mg/1cap 2 tablets, take medication an hour before surgery

PROCEDURE

Preoperative peritoneal biopsy

Preoperative peritoneal biopsy (1x1cm sized peritoneal tissue)

PROCEDURE

Single-port laparoscopic surgery

Single-port laparoscopic surgery with CO2 gas

PROCEDURE

Postoperative peritoneal biopsy

Postoperative peritoneal biopsy (1x1cm sized peritoneal tissue)

Sponsors & Collaborators

  • Seoul National University Hospital

    lead OTHER

Principal Investigators

  • Hee Seung Kim, PhD · Seoul National University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-17
Primary Completion
2019-10-31
Completion
2019-10-31

Countries

  • South Korea

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03391570 on ClinicalTrials.gov