Computerized Response Training Obesity Treatment

Summary

This project will test whether a food response training intervention produces lasting body fat loss, use objective brain imaging to examine the mechanism of effect of this treatment and investigate the generalizability of the training to non-training foods, and examine factors that should amplify intervention effects to provide a test of the intervention theory. This novel treatment represents a bottom-up implicit training intervention that does not rely on executive control, prolonged caloric deprivation, and expensive clinicians to deliver, like behavioral weight loss treatments that have not produced lasting weight loss. If this computer-based response training intervention produces sustained body fat loss in overweight individuals, it could be easily implemented very broadly at almost no expense, addressing a leading public health problem.

Conditions

• Obesity
• Hyperphagia
• Feeding and Eating Disorders

Interventions

BEHAVIORAL

Computer Based Response Training Weight Loss Intervention

Participants complete four computer based training tasks each visit, over the course of a few lab visits. Participants then perform weekly booster sessions in a more natural home or community environment over the internet using the same computer based training tasks.

BEHAVIORAL

Generic Response Training Control Intervention

Participants complete four computer based training tasks each visit, over the course of a few lab visits. Participants then perform weekly booster sessions in a more natural home or community environment over the internet using the same computer based training tasks.

Sponsors & Collaborators

• Flinders University

  collaborator OTHER

• University of Exeter

  collaborator OTHER

• Radboud University Medical Center

  collaborator OTHER

• University of Oregon

  collaborator OTHER

• Oregon Research Institute

  lead OTHER

Principal Investigators

• Eric Stice, PhD · Stanford University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

38 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-07-15

Primary Completion

2023-08-31

Completion

2023-09-15

Countries

• United States

Study Locations