Imatinib for Cytomegalovirus Prophylaxis and Treatment After Allogeneic Hematopoietic Stem Cell Transplantation

NCT03343600 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 5

Last updated 2019-09-11

No results posted yet for this study

Summary

This study aim at examining whether blocking platelet-derived growth factor receptor-α by imatinib lowers the risk of post-allogeneic hematopoietic stem cell transplantation CMV infection.

Conditions

  • Patients Who Have Received Allo-HSCT

Interventions

DRUG

Imatinib

Imatinib 100 mg/tablet, 2 tablets daily

DRUG

Placebo

Placebos 2 tablets daily

Sponsors & Collaborators

  • Far Eastern Memorial Hospital

    collaborator OTHER
  • Tri-Service General Hospital

    collaborator OTHER
  • National Cheng-Kung University Hospital

    collaborator OTHER
  • Hualien Tzu Chi General Hospital

    collaborator OTHER
  • National Taiwan University Hospital

    lead OTHER

Principal Investigators

  • Chien-Ting Lin, MD · National Taiwan University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-11-09
Primary Completion
2019-08-31
Completion
2019-08-31

Countries

  • Taiwan

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03343600 on ClinicalTrials.gov