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Local Anesthetic Concentration and Nerve Block Duration

NCT03326609 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2018-01-08

No results posted yet for this study

Summary

Background: Local anesthetic (LA) concentration and nerve block duration is sparsely described in a heterogenic study mass.

Aim: To investigate the effect of LA concentration on peripheral nerve block duration in healthy volunteers.

Methods: Randomization of 60 healthy volunteers who will receive 1 of 5 different volumes of LA (ropivacaine) using a constant dose.

Primary endpoint: Sensory nerve block defined by insensitivity towards cold.

Conditions

  • Peripheral Nerve Block

Interventions

DRUG

Ropivacaine

Perineural injection using a peripheral nerve block catheter and a constant infusion rate (10mL/h)

Sponsors & Collaborators

  • Innovation Fund Denmark

    collaborator INDIV

  • Nordsjaellands Hospital

    lead OTHER

Principal Investigators

  • Claus B Christiansen, MD · Nordsjaellands Hospital

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-10-04
Primary Completion
2017-12-08
Completion
2018-01-05

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03326609 on ClinicalTrials.gov