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Influence of Different PEEP Levels and Tidal Volumes on Regional Lung Function

NCT03326414 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2017-10-31

No results posted yet for this study

Summary

Mechanical ventilation is indispensable for most of surgical interventions but can induce lung injury even in pulmonary healthy patients. This can lead to postoperative pulmonary complications. These adverse effects could be prevented by a better monitoring of intraoperative lung function. Electrical impedance tomography is able to visualize aeration within the lung in real time.

The planned study investigates the influence of different levels of positive endexspiratory pressure and different tidal volumes on the aeration.

Conditions

  • Pulmonary Ventilation; Newborn, Abnormal

Interventions

PROCEDURE

Constant PEEP - low tidal volume

The respirator is set according to study protocol

PROCEDURE

Constant PEEP - high tidal volume

The respirator is set according to study protocol

PROCEDURE

constant tidal volume - low PEEP

The respirator is set according to study protocol

PROCEDURE

constant tidal volume - high PEEP

The respirator is set according to study protocol

Sponsors & Collaborators

  • Universitätsklinikum Hamburg-Eppendorf

    lead OTHER

Principal Investigators

  • Daniel A Reuter, MD · Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Germany

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-31
Primary Completion
2018-04-30
Completion
2018-06-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03326414 on ClinicalTrials.gov