MedTrace Logo

Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study

NCT03323164 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 35

Last updated 2020-12-31

Study results available
· View outcomes & findings →

Summary

This study evaluates the possible acute changes in peripapillary blood flow after instillation of antiglaucoma medications in patients with primary open angle glaucoma (POAG), normal tension glaucoma (NTG), or ocular hypertension (OHTN) using Optical Coherence Tomography (OCT) angiography.

Conditions

  • Glaucoma; Drugs
  • Normal Tension Glaucoma
  • Primary Open-angle Glaucoma

Interventions

DRUG

Timolol Maleate

Instillation of one drop in each eye, one-time. Obtaining of OCT angiography scans after 2 hours of instillation.

DRUG

Brimonidine Tartrate

Instillation of one drop in each eye, one-time. Obtaining of OCT angiography scans after 2 hours of instillation.

Sponsors & Collaborators

  • Optovue

    collaborator INDUSTRY

  • Wills Eye

    lead OTHER

Principal Investigators

  • Daniel Lee, MD · Wills Eye Hospital

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-07-10
Primary Completion
2018-12-31
Completion
2020-05-30
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03323164 on ClinicalTrials.gov