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Effect of Antiglaucoma Agents on Short Term Intraocular Pressure Fluctuations After Intravitreal Bevacizumab Injection

NCT02140450 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2014-05-16

No results posted yet for this study

Summary

To assess the effect of prophylactic antiglaucoma agents in prevention of acute intraocular pressure rise after intravitreal injection.

Conditions

  • Intraocular Pressure Change in Intravitreal Injection

Interventions

DRUG

Timolol

2 drops of timolol, 10 minutes apart, 1-2 hours before intravitreal injection

DRUG

Brimonidine

Brimonidine eyedrop, 2 drops 5 minutes apart, 1-2 hours before intravitreal injection

DRUG

Acetazolamide

Acetazolamide tablet, 2 tabs, 2 hours before intravitreal injection

DRUG

Mannitol

Intravenous mannitol, 1.5 gram/kg, 1 hour before intravitreal injection

DRUG

Placebo

Artificial tears, 2 drops, 1-2 hours before intravitreal injection

Sponsors & Collaborators

  • Mashhad University of Medical Sciences

    lead OTHER

Principal Investigators

  • Nasser Shoeibi, M.D. · Retina Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-02-29
Primary Completion
2014-01-31
Completion
2014-05-31

Countries

  • Iran

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02140450 on ClinicalTrials.gov