Sarcopenia in Axial and Peripheral Spondyloarthropathies

Summary

Spondylarthropathies (SpA) are among the most common chronic inflammatory rheumatisms in adults, responsible for a muscular loss or sarcopenia which can be very disabling, not much documented in the literature, and not yet studied in France. In addition, sarcopenia is associated with decreased physical activity and increased risk of falls and fractures. A better characterization of the determinants of this muscular loss will allow to better detect and take care of it.

The aim is to conduct the first French study on the prevalence and severity of sarcopenia in patients with spondyloarthropathies and to study the variables that may be associated with it. Finally, we propose to evaluate obesity related to sarcopenia in these patients and compare them to cases matched for age and sex (from OFELY / STRAMBO cohorts, Lyon, FRANCE).

This is a prospective interventional and monocentric study with minimal risks and constraints: patients will be included for one day for an evaluation of their sarcopenia by measuring their muscle strength, physical performance and body composition and recording of their socio-demographic and disease characteristics.

Conditions

• Spondylarthropathy
• Sarcopenia

Interventions

OTHER

Dynamometry exam

Prehension strength of the main hand will be assessed thanks to dynamometry, in order to evaluate patient's muscular strength

OTHER

Walking test

A 4 metres walking test will be performed to assess patient's walking speed

RADIATION

DXA measurement

DXA measurement will be performed to assess patient's body composition

OTHER

SARQOL questionnaire

Patient's quality of life will be assessed thanks to the SARQOL questionnaire

BEHAVIORAL

Life habits Questionnaire

Life habits Questionnaire

Sponsors & Collaborators

• Hospices Civils de Lyon

  lead OTHER

Study Design

Allocation

NA

Purpose

SCREENING

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-11-02

Primary Completion

2018-07-04

Completion

2018-07-04

Countries

• France

Study Locations