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Pregnancy, Nitrate, Endothelial Function and Tissue Oxygen Saturation

NCT03315806 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2024-12-18

No results posted yet for this study

Summary

Adequate macro and microvascular endothelial function during pregnancy is essential for the normal placental development and growing fetus. Beetroot juice (BJ) promotes improvement ins this parameters in no-pregnant individuals, however the beneficial effect did not avaliated in pregnant. The present study evaluated effects of BJ on macro and microvascular endothelial function in pregnant. Twelve pregnant were submitted to BJ and nitrate-depleted juice (PLA) interventions. Brachial flow-mediated dilation (FMD) and muscle oxygenation were measured 120 min after interventions. Urinary nitrate, nitrite were measured at baseline and 120 min after interventions.

Conditions

  • Pregnancy

Interventions

OTHER

Beetroot juice

140 mL of beetroot juice cointaning approximately 9 mmol of nitrate

OTHER

Placebo

140 mL of beetroot juice isent of nitrate

Sponsors & Collaborators

  • Universidade Federal do Rio de Janeiro

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-10-06
Primary Completion
2017-02-14
Completion
2017-05-19

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03315806 on ClinicalTrials.gov