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Distribution of Smooth Muscle In Dartos In The Non Conspicuous Penis

NCT03295175 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2024-03-13

No results posted yet for this study

Summary

Non-conspicuous penis (congenital megaprepuce, occult penis) is a symptomatic malformation that includes phimosis and excessively baggy, urine-filled prepuce with alteration of the appearance of the penis. A redundant and enlarged foreskin is the main feature of this entity.This congenital anomaly is difficult to diagnose and may have association with other pathologies such as buried penis.

Currently, part of the megaprepuce skin is used to correct the defect. A recent study shows that patients with this pathology and hypospadias present mostly defects in the muscle dartos. The investigators do not know the physiological bases of the megaprepuce, neither the clinical and aesthetics implications of this abnormal tissue for the patient, and how this affects the postoperative evolution. With the present study the investigators intended to answer these questions and to open paths for future research in this area.

Conditions

  • Congenital Urogenital Anomaly

Interventions

DIAGNOSTIC_TEST

Hematoxylin-eosin and smooth muscle actin markers

The foreskin arrives oriented in a single piece in formol to the unit of pathology, and in the pathology unit, they must: 1. Measure the length, width and thickness of the specimen. The specimen should include skin and mucosa with the underlying areolar tissue. 2. Examine the surfaces of the sample searching lesions, and describe them in size, appearance (warty, papillary, ulcerated), depth of invasion, and distance from the nearest cutting edge, if they are present.

Sponsors & Collaborators

  • Hospital Universitario San Ignacio

    lead OTHER

Principal Investigators

  • Jose N Fernandez, MD · H

Eligibility

Min Age
1 Month
Max Age
10 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-21
Primary Completion
2024-03-12
Completion
2024-03-12

Countries

  • Colombia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03295175 on ClinicalTrials.gov