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Exploration of eJaculatory Anatomy Concept Study (EJAC Study)

NCT05650853 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 3

Last updated 2026-03-06

No results posted yet for this study

Summary

Ejaculatory dysfunctions (ED) are an important cause of postoperative dissatisfaction, which lead to a decrease in the intensity of orgasms in 50% of patients. ED is a cause for concern for almost a third of patients who need surgery. Surgical techniques have been developed to limit the occurrence of postoperative ED, but their results remain heterogeneous.

There are very few studies on the biomechanical anatomy of ejaculation. Ejaculation is a complex phenomenon involving different structures and in particular the Veru Montanum. This is the key element in the emission of ejaculate within the prostatic urethra. In addition, there is a structure located in the resection zone of the prostate adenoma. It has therefore been suggested that its resection was a primary source of ED.

A single observational study carried out in by Gil Vernet et al in 1994 evaluated on a single healthy 18-year-old volunteer the ejaculatory mechanism of expulsion using an endorectal probe recording the movements of the prostate, the bladder neck and of the proximal urethra during ejaculation.

A contemporary study of the biomechanics of the ejaculatory expulsion phase could confirm and improve understanding of the involvement of anatomical structures. The results of our study aim to adapt surgical techniques aimed at limiting the risk of postoperative ED.

Conditions

  • Ejaculatory Dysfunction

Interventions

OTHER

Transrectal ultrasound

Examinations for observation of the pre, per and post-ejaculatory phases

OTHER

Urethroscopy

Examinations for observation of the pre, per and post-ejaculatory phases

Sponsors & Collaborators

  • Clinique Pasteur

    lead OTHER

Principal Investigators

  • Benjamin Pradère, MD · Clinique La Croix du Sud

  • Eric Bruguière, MD · Clinique Pasteur

  • Vincent Misraï, MD · Clinique Pasteur

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-12-12
Primary Completion
2023-01-09
Completion
2023-01-09

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05650853 on ClinicalTrials.gov