Ultra High Field Magnetic Resonance Imaging as a Biomarker for Premotor Parkinson's Disease
NCT03288909 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 18
Last updated 2019-06-24
Summary
This is a prospective observational study investigating the utility of 7 Tesla MRI to quantify nigrosome1 signal in a cohort of individuals with recent onset Parkinson's disease and in at-risk cohorts at a premotor state of Parkinson's disease.
Conditions
- Parkinson Disease
- REM Sleep Behavior Disorder
Interventions
- OTHER
-
MRI
Sponsors & Collaborators
-
Oregon Health and Science University
lead OTHER
Principal Investigators
-
Matthew Brodsky, MD · Oregon Health and Science University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-09-30
- Primary Completion
- 2020-01-31
- Completion
- 2021-01-31
Countries
- United States
Study Locations
More Related Trials
-
Longitudinal TSPO PET Imaging With [18F]DPA-714 in PPMI (PPMI DPA-714 PET Imaging)
NCT06289582 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Magnetic Resonance Imaging (MRI) of Brain Iron in Neurodegenerative Disease
NCT00249080 ·Status: COMPLETED
-
Non-Heme Iron Load Quantification in the Brain - MRI of Patients With Stroke
NCT01829386 ·Status: COMPLETED
-
Functional Neuroimaging in Parkinson's Disease
NCT04904068 ·Status: COMPLETED
-
Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)
NCT07265596 ·Status: RECRUITING ·Phase: PHASE2
-
The GBA Multimodal Study in Parkinson's Disease
NCT04101968 ·Status: RECRUITING
-
Brain Sleep Deprivation MRI Effects (BEDTIME)
NCT02741505 ·Status: WITHDRAWN ·Phase: NA
-
Brain Iron Toxicity and Neurodegeneration - A 7T MRI Study
NCT04992975 ·Status: RECRUITING
-
Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects
NCT02103894 ·Status: COMPLETED ·Phase: PHASE1
-
Precision Medical Diagnosis for Parkinson's Disease - The Quantitative Analysis System for PET/MRI Images in Patients
NCT03909828 ·Status: UNKNOWN
-
Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis
NCT00321568 ·Status: COMPLETED
-
Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis
NCT00393588 ·Status: COMPLETED
-
Quantitative Imaging and Proton Spectroscopy in Multiple Sclerosis
NCT01226654 ·Status: TERMINATED ·Phase: NA
-
Magnetic Resonance Imaging Studies of Motor and Thought Processes
NCT00001361 ·Status: COMPLETED
-
Evaluation of [18F] PBR06 and PET as a Marker of Inflammation in Subjects With Neurological Conditions
NCT01028209 ·Status: TERMINATED ·Phase: PHASE1
-
Multimodal Markers of Neurodegenerative Disorders at Presymptomatic Stages
NCT06516016 ·Status: NOT_YET_RECRUITING
-
Refinement and Assessment of New Magnetic Resonance Imaging Technologies for Neurological Exams
NCT00739518 ·Status: COMPLETED ·Phase: NA
-
Imaging Blood Brain Imaging Dysfunction in Parkinson's Disease
NCT02605161 ·Status: COMPLETED
-
Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis
NCT00099307 ·Status: COMPLETED
-
Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study
NCT02868684 ·Status: COMPLETED
-
New Imaging Biomarkers Predictive of MA Progression
NCT05939362 ·Status: RECRUITING ·Phase: NA
-
Molecular and Functional Imaging in Monogenic PD.
NCT05518617 ·Status: RECRUITING
-
2-(1-{6-[(2-[F-18]Fluoroethyl) (Methyl)Amino]-2-naphthyl} Ethylidene) Malononitrile-PET for in Vivo Diagnose of Tauopathy in Unclassified Parkinsonism
NCT02214862 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
PPMI Tau PET Imaging
NCT04906590 ·Status: COMPLETED ·Phase: PHASE2
-
Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System
NCT03270059 ·Status: RECRUITING ·Phase: PHASE2