Enabling Personalized Medicine Through Exome Sequencing in the U.S. Air Force
NCT03276637 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 105
Last updated 2024-10-02
Summary
The MilSeq Project is a nonrandomized, prospective pilot study of whole exome sequencing (WES) in the U.S. Air Force. The purpose of this study is to explore the implementation of WES into clinical medical care in the military health system.
Conditions
- Healthy Adults
- Genetic Predisposition to Disease
Interventions
- GENETIC
-
Whole exome sequencing
Whole exome sequencing at 125x coverage (i.e., at least 125 sequencing reads covering each position within the exome region of interest) performed at the Laboratory of Molecular Medicine's Clinical Laboratory Improvement Amendments (CLIA) certified laboratory on 75 enrolled individuals
Sponsors & Collaborators
-
United States Department of Defense
collaborator FED -
Brigham and Women's Hospital
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-08-23
- Primary Completion
- 2019-06-22
- Completion
- 2020-01-11
Countries
- United States
Study Locations
More Related Trials
-
Molecular Diagnosis of Syndromic or Isolated Severe Intellectual Disability Using Whole Exome Sequencing : a Pilot Study
NCT02862808 ·Status: COMPLETED
-
A Study of Consent Forms for Whole Exome and Whole Genome Sequencing
NCT01927770 ·Status: COMPLETED
-
IPGx PILOT Whole Genome Sequencing Extension Cohort
NCT06766071 ·Status: RECRUITING
-
Observational Study of Advanced Data Analytics in Genetic Conditions
NCT05657405 ·Status: RECRUITING
-
Clinical Implementation of Carrier Status Using Next Generation Sequencing
NCT01902901 ·Status: COMPLETED ·Phase: NA
-
Pharmacogenetic Testing in Primary Care
NCT01600846 ·Status: COMPLETED
-
Pediatric Reporting of Adult-Onset Genomic Results
NCT03832985 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Genomic Sequencing for Childhood Risk and Newborn Illness
NCT02422511 ·Status: COMPLETED ·Phase: NA
-
Patient and Healthcare Professional Views on Genetic/Genomic Information and Testing
NCT04733274 ·Status: ACTIVE_NOT_RECRUITING
-
Integrative Sequencing In Germline and Hereditary Tumours
NCT03857594 ·Status: ACTIVE_NOT_RECRUITING
-
NeuroSeq: A Prospective Trial to Evaluate the Diagnostic Yield of Whole Genome Sequencing (WGS) in Adult Neurology
NCT04170985 ·Status: COMPLETED
-
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions
NCT02077894 ·Status: RECRUITING
-
Diagnostic Odyssey: Whole Genome Sequencing (WGS)
NCT03458962 ·Status: RECRUITING
-
Genetic Analysis of Uncommon Disease Presentations in Non-US Populations
NCT06595940 ·Status: RECRUITING
-
Omics Gaucher Study: Multiomic Approach
NCT05526664 ·Status: ACTIVE_NOT_RECRUITING
-
Exome and Genome Analysis to Elucidate Genetic Etiologies and Population Characteristics in the Plain Community
NCT02927158 ·Status: RECRUITING
-
Study of Clinical and Molecular Manifestations of Genetic Disorders
NCT00001466 ·Status: COMPLETED
-
Research for Individualized Therapeutics in Rare Genetic Disease
NCT05236595 ·Status: ENROLLING_BY_INVITATION
-
Clinical Integration of Genetic Risk Assessment in Family Medicine
NCT00339794 ·Status: COMPLETED
-
Genetic Counselors' Experiences of Moral Value Conflicts With Clients
NCT00360711 ·Status: COMPLETED
-
Genetic Variability in CYP2D6 in U.S Active Duty Population
NCT02960568 ·Status: COMPLETED ·Phase: PHASE1
-
Patient and Provider Confidence and Satisfaction With the Clinical Use of CYP Genetic Variability
NCT02568618 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Educational Video for Genetic Testing
NCT05472714 ·Status: COMPLETED ·Phase: NA
-
Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight
NCT01238250 ·Status: RECRUITING
-
Refining Information Technology Support for Genetics in Medicine
NCT01225978 ·Status: UNKNOWN