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Vascular and Metabolic Changes in Postmenopausal Diabetics

NCT03273738 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2018-06-27

No results posted yet for this study

Summary

The presence of type 2 diabetes mellitus (T2DM) also increases the relative risk of developing cardiovascular disease in women compared to men. Carotid intima media thickness (IMTc) was increased with reduction in brachial artery flow-mediated dilation (FMD) in T2 DM patients and inversely and strongly related to the extent of hyperglycemia. Low concentrations of folate and vitamin B12 involved in homocysteine metabolism are also associated with increased risk of vascular damage. the aim is to relate, if found, the degree of metabolic changes to the extent in vascular parameters changes in type 2 diabetic postmenopausal women.

Conditions

  • Diabete Type 2

Interventions

DIAGNOSTIC_TEST

folate level measurement

the level of folate measured in plasma with homocysteine

DIAGNOSTIC_TEST

B12

B12 measurement in blood

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Lobna F Eltoony · internal medicine

Eligibility

Min Age
50 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-10-02
Primary Completion
2018-10-10
Completion
2018-11-15

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03273738 on ClinicalTrials.gov