Ascorbic Acid Versus Diode Laser in the Treatment of Gingival Hyperpigmentation
NCT03252418 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2017-08-22
Summary
Vitamin C affect the melanocytes function not the number while diode laser cause melanocytes destruction. Although diode laser and vitamin C have proved their effectiveness in depigmentation in previous studies, there are no published studies compared the effect of diode laser and vitamin C on melanocytes and melanosomes clinically and histologically.
Conditions
- Gingival Hyperpigmentaion
Interventions
- DRUG
-
Ascorbic Acid 500 MG
ascorbic acid is vitamin that can cause gingival depigmentation
- DEVICE
-
diode laser
diode laser is soft tissue laser case photothermolysis of melanoctes
Sponsors & Collaborators
-
Ain Shams University
lead OTHER
Principal Investigators
-
Nevine H kheir ElDien, Professor · faculty of Dentistry- Ain Shams univesity
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-10-07
- Primary Completion
- 2016-09-10
- Completion
- 2016-09-10
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